Investigating Direct Access to 2??Oxospiro [4.5] decanones via 6π??Electrocyclisation

…, H Schill, CM Williams, PV Bernhardt

文献索引：Pouwer, Rebecca H.; Schill, Heiko; Williams, Craig M.; Bernhardt, Paul V. European Journal of Organic Chemistry, 2007 , # 28 p. 4699 - 4705

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被引用次数: 11

摘要

Abstract The 2-oxospiro [4.5] decan-1-one (or spiro-γ-lactone) structural motif is contained within a number of natural products, for example, the clerodane family of diterpenes. Methods to construct this structural motif are somewhat limited and usually involve multiple functional group interconversions. A novel synthetic approach to this system utilising 6π- electrocyclisation has been identified and associated density functional calculations ...