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Stereoselective synthesis of nicotinamide β-riboside and nucleoside analogs

…, R Petrelli, M Ricciutelli, P Vita, L Cappellacci

文献索引:Franchetti, Palmarisa; Pasqualini, Michela; Petrelli, Riccardo; Ricciutelli, Massimo; Vita, Patrizia; Cappellacci, Loredana Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 18 p. 4655 - 4658

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被引用次数: 19

摘要

The β-anomers of N-ribofuranosylnicotine-3-carboxamide (β-NAR) and its nicotinic acid analog (β-NaR) were obtained by stereoselective synthesis via glycosylation of the presilylated bases under Vorbruggen's protocol. A NAR analog, methylated in position 3 of the ribosylic moiety, is also reported.