Organic letters

Synthesis of Small and Large Fused Bicyclic Compounds by Tandem Dienyne Ring-Closing Metathesis

H Park, YL Hong, YB Kim, TL Choi

文献索引：Park, Hyeon; Hong, You-Lee; Kim, Yongjoo B.; Choi, Tae-Lim Organic Letters, 2010 , vol. 12, # 15 p. 3442 - 3445

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被引用次数: 22

摘要

A tandem ring-closing metathesis reaction using ruthenium catalyst was carried out to synthesize various fused bicyclic compounds containing both small and large rings. Fast ring-closure of the small ring and slow ring-closure of the large ring resulted in the formation of only one isomer. Further manipulation such as the Diels− Alder reaction was carried out to prepare a complex molecule containing multiple rings of different sizes.