2-thenyl substituted diamines with antihistaminic activity

F Leonard, UV Solmssen

文献索引：Leonard; Solmssen Journal of the American Chemical Society, 1948 , vol. 70, p. 2064,2066

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被引用次数: 18

摘要

A number of aminoalkyl ethers and alkylenediamines which exhibit antihistaminic activity have been discovered1 and several have been adopted for clinical use. Since these substances are not without their undesirable side effects we DreDared a series of 2-thenvl substituted alkvlenehiahnes which conform4 to the general'type c4HaSCH*>~-~ 2~. where RI is phenyl or 2-py-R, ridyl, R; is a straight or branched alkylene chain containing two or ...