Synthesis and antifungal activity of coumarins and angular furanocoumarins

…, RG Micetich, S Nishibe, M Daneshtalab

文献索引：Sardari, Soroush; Mori, Yoki; Horita, Kiyoshi; Micetich, Ronald G.; Nishibe, Sansei; Daneshtalab, Mohsen Bioorganic and Medicinal Chemistry, 1999 , vol. 7, # 9 p. 1933 - 1940

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被引用次数: 255

摘要

Angelicin, a naturally occurring furanocoumarin, that showed antifungal activity, was considered as a lead structure for a group of synthetic coumarins. Antifungal activities of the synthesized coumarins and angelicin derivatives were reported against Candida albicans, Cryptococcus neoformans, Saccharomyces cerevisiae and Aspergillus niger. Human cell line cytotoxicity of several coumarins was evaluated against KB cells. Angelicin and ...