Tetrahedron

Stereocontrolled total synthesis of (±)-totaryl methyl ether and (±)-semperviryl methyl ether

S Das, B Sukanta, M Debabrata

文献索引：Das, Swati; Bhattachryya, Sukanta; Mukherjee, Debabrata Tetrahedron, 1992 , vol. 48, # 41 p. 9101 - 9110

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被引用次数: 3

摘要

Stereocontrolled synthesis in racemic form of the title diterpene ethers is described. Friedel- Crafts acylation of the naphthalene derivative 15 afforded the methyl ketone 16 in high yield. The compounds 5 and 16 were converted into the hydrophenanthrenones 6 and 7 respectively. Reductive methylation of 6 and 7 in anhydrous ammonia furnished the β, γ- unsaturated ketones 8 and 9 which were stereoselectively transformed into the trans- ...