Tetrahedron

A new asymmetric synthetic route to substituted piperidines

MS Reddy, M Narender, KR Rao

文献索引：Reddy, M. Somi; Narender; Rao, K. Rama Tetrahedron, 2007 , vol. 63, # 2 p. 331 - 336

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被引用次数: 26

摘要

An asymmetric synthesis of substituted piperidines has been described. β-Cyclodextrin-or oxazaborolidine-catalyzed asymmetric reduction of α-azido aryl ketones to the corresponding alcohols has been employed as the key step along with ring closing metathesis and selective dihydroxylation.