New 5H-1, 2, 4-triazino [5, 6-b] indole and aminoindole derivatives. Synthesis and studies as inhibitors of blood platelet aggregation, anti-hypertensive agents and …
…, C Ramirez, M Font, E Fernandez-Alvarez
文献索引：Monge; Palop; Ramirez; Font; Fernandez-Alvarez European Journal of Medicinal Chemistry, 1991 , vol. 26, # 2 p. 179 - 188
Abstract This paper reports the synthesis of a series of 5H-1, 2, 4-triazino [5, 6-b] indole 3 and 4, and aminoindole 12–23, derivatives, obtained from isatin 1 and from oxoindole 5, respectively. All the new compounds were studied as antihypertensive agents in spontaneously hypertensive rats (SHR), and as inhibitors of platelet aggregation in guinea pig whole blood, induced by arachidonic acid (AA), adenosin-5′-diphosphate (ADP) or ...
