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A novel ring-opening reaction. An improved method for reductive succinoylation

E Nakamura, K Hashimoto…

文献索引:Nakamura,E. et al. Journal of Organic Chemistry, 1977 , vol. 42, p. 4166 - 4167

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被引用次数: 16

摘要

Summary: In the presence of stannic chloride, l, 2-bis (tri-methylsi1oxy)-1-cyclobutene and a ketal undergo two successive reactions, aldol and a new ring cleavage reaction, to give an enol silyl ether of y-keto ester: the overall reaction represents a new, single-pot reductive succinoylation method.