One-pot synthesis of 4-methylisoquinolines via a sequential Pd-catalyzed Heck reaction and intramolecular cyclization

Y Tian, J Qi, C Sun, D Yin, X Wang…

文献索引：Tian, Yulin; Qi, Jianguo; Sun, Chenbin; Yin, Dali; Wang, Xiaojian; Xiao, Qiong Organic and Biomolecular Chemistry, 2013 , vol. 11, # 42 p. 7262 - 7266

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被引用次数: 4

摘要

An efficient, one-pot synthesis of 4-methylisoquinolines via a cascade Pd-catalyzed Heck reaction, intramolecular cyclization and isomerization has been developed. This reaction has a wide range of substrates with various functional groups, and the corresponding products have been obtained in good yields.