Tetrahedron Letters

A novel one-pot synthesis of 2-benzoylpyrroles from benzaldehydes

R Sharma, M Chouhan, VA Nair

文献索引：Sharma, Ratnesh; Chouhan, Mangilal; Nair, Vipin A. Tetrahedron Letters, 2010 , vol. 51, # 15 p. 2039 - 2043

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被引用次数: 19

摘要

Pyrrole 1 is the core unit of many therapeutically active molecules such as tolmetin, atorvastatin, chlorfenapyr, premazepam, pyrvinium, roseophilin, zomepirac and natural products such as bilins, bilanes, phycobilin, porphyrin and chlorophyll. 2 Synthesis of pyrrole derivatives involves two types of strategies: (a) condensation reactions of α-aminocarbonyl compounds and activated ketones (Knorr pyrrole synthesis 3 ) or α-halocarbonyl compounds, β-keto ...