Tetrahedron letters

Linear free energy relationships of the inhibition of pancreatic cholesterol esterase by 4-nitrophenyl-N-alkylcarbamate

G Lin, CY Lai

文献索引：Lin, Gialih; Lai, Cheng-Yue Tetrahedron Letters, 1996 , vol. 37, # 2 p. 193 - 196

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被引用次数: 28

摘要

4-Nitrophenyl-N-alkylcarbamates (1) as active site-directed irreversible inhibitors of pancreatic cholesterol esterase are investigated for values of the dissociation constant (Ki), the carbamylation constant (k2), and the bimolecular rate constant (ki). Linear free energy