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6-(Het) aryl-7-deazapurine ribonucleosides as novel potent cytostatic agents

P Nauš, R Pohl, I Votruba, P Džubák…

文献索引:Silhar, Peter; Pohl, Radek; Votruba, Ivan; Hocek, Michal Collection of Czechoslovak Chemical Communications, 2005 , vol. 70, # 10 p. 1669 - 1695

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被引用次数: 68

摘要

A series of novel 7-deazapurine ribonucleosides bearing an alkyl, aryl, or hetaryl group in position 6 and H, F, or Cl atom in position 7 has been prepared either by Pd-catalyzed cross- coupling reactions of the corresponding protected 6-chloro-(7-halogenated-) 7-deazapurine