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A simple and regioselective α-bromination of alkyl aromatic compounds by two-phase electrolysis

T Raju, K Kulangiappar, MA Kulandainathan…

文献索引：Raju; Kulangiappar; Anbu Kulandainathan; Muthukumaran Tetrahedron Letters, 2005 , vol. 46, # 41 p. 7047 - 7050

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被引用次数: 16

摘要

Electrochemical bromination of toluene and substituted toluenes by two-phase electrolysis yields the corresponding α-brominated products. The reaction has been carried out in a single compartment cell with platinum electrodes at 0° C in chloroform using an aqueous sodium bromide solution (60%) containing a catalytic amount of HBr. Two-phase electrolysis results in high yields (60–95%) of monobromo compounds with very high regioselectivity ( ...