Discovery of Functionally Selective 7, 8, 9, 10-Tetrahydro-7, 10-ethano-1, 2, 4-triazolo [3, 4-a] phthalazines as GABAA Receptor Agonists at the α3 Subunit

MGN Russell, RW Carling, JR Atack…

文献索引：Journal of Medicinal Chemistry, , vol. 48, # 5 p. 1367 - 1383

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被引用次数: 40

摘要

... Journal of Medicinal Chemistry. ... Chemistry. The final compounds were all synthesized through the 3-substituted 6-chloro-7,8,9,10-tetrahydro-7,10-ethano- 1,2,4-triazolo[3,4-a]phthalazines (101a−p) (Scheme 1). These ...