Tetrahedron letters

Calcium-promoted hydrolysis of N-acylureas allows mild release of peptides anchored with the Dpr (Phoc) linker to hydrophilic resins

R Pascal, R Soda

文献索引：Pascal, Robert; Sola, Regine Tetrahedron Letters, 1997 , vol. 38, # 26 p. 4549 - 4552

全文：HTML全文

被引用次数: 13

摘要

Calcium chloride is an efficient additive for promoting the release of short peptide models anchored with Dpr (Phoc) linker to hydrophilic solid-phase synthesis supports. It was shown to induce a moderate to marked (especially for C-terminal proline peptides) increase in the