Synthesis and Antibacterial Activity of Bis [2-amino-4-phenyl-5-thiazolyl] Disulfides

HL Siddiqui, M Zia-ur-Rehman, N Ahmad…

文献索引：Siddiqui, Hamid Latif; Zia-Ur-Rehman, Muhammad; Ahmad, Naveed; Weaver, George William; Lucas, Paul David Chemical and Pharmaceutical Bulletin, 2007 , vol. 55, # 7 p. 1014 - 1017

全文：HTML全文

被引用次数: 25

摘要

Different dimeric disulfides, having the basic skeleton of bis [2-amino-4-phenyl-5-thiazolyl] disulfides were synthesized in a straightforward manner from acetophenones. 2-Amino-4- phenyl-1, 3-thiazoles were prepared by the reaction of thiourea with substituted acetophenones in the presence of iodine which were then converted to the title compounds. All the compounds were subjected to preliminary evaluation for their biological activity ...