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The application of phenylmethanethiol and benzenethiol derivatives as odorless organosulfur reagents in the synthesis of thiosugars and thioglycosides

J Hasegawa, M Hamada, T Miyamoto, K Nishide…

文献索引:Hasegawa, Jun-Ya; Hamada, Masahiro; Miyamoto, Tetsuo; Nishide, Kiyoharu; Kajimoto, Tetsuya; Uenishi, Jun-Ichi; Node, Manabu Carbohydrate Research, 2005 , vol. 340, # 15 p. 2360 - 2368

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被引用次数: 25

摘要

Thiosugars, in which the ring oxygen of the monosaccharide is replaced with a sulfur atom, have been utilized in the synthesis of bioactive oligosaccharides as excellent analogs of monosaccharides because of their tolerant reactivity with glycosidases. 1 Naturally occurring thiosugar derivatives, as well as synthesized derivatives, show inhibitory activity against glycosidases, for example, salacinol isolated from Salacia reticulata is a potent inhibitor of ...