Alkoxyamino glycoside acceptors for the regioselective synthesis of oligosaccharides using glycosynthases and transglycosidases

…, F Daligault, V Tran, C André-Miral, C Tellier

文献索引：Teze, David; Dion, Michel; Daligault, Franck; Tran, Vinh; Andre-Miral, Corinne; Tellier, Charles Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 2 p. 448 - 451

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被引用次数: 8

摘要

Alkoxyamino derivatives of oligosaccharides have been synthesized by enzymatic synthesis using a glycosynthase and a transglycosidase. The chemoselective assembly of unprotected oligosaccharides bearing glucose at the reducing end with N-alkyl-O- benzylhydroxylamine provides sugar derivatives that are good acceptors for enzymatic synthesis using either glycosynthase or transglycosidase. Furthermore, this method ...