Synthesis and Antimicrobial Activity of N, N'-Bis (2-hydroxylbenzyl)-1, 2-ethanediamine Derivatives

…, A Aspedon, JS Cooperwood

文献索引：Musa, Musiliyu A.; Khan, M. Omar F.; Aspedon, Arden; Cooperwood, John S. Letters in Drug Design and Discovery, 2010 , vol. 7, # 3 p. 165 - 170

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被引用次数: 12

摘要

A series of N, N'-Bis (2-hydroxylbenzyl)-1, 2-ethanediamine derivatives and its schiff bases were synthesized, characterized and screened for in vitro antimicrobial activity against Staphylococcus aureus, Pseudomonas aeruginosa and Salmonella enterica. Result indicated that the ethylenediamine derivatives, N, N'-Bis (2-hydroxy-5-bromobenzyl)-1, 2- ethanediamine (21), and N, N'-Bis (2-hydroxy-5-chlorobenzyl)-1, 2-ethanediamine (22) ...