synthesis

Synthesis of furanomycin derivatives by Gold-catalyzed cycloisomerization of α-hydroxyallenes

J Erdsack, N Krause

文献索引：Erdsack, Joerg; Krause, Norbert Synthesis, 2007 , # 23 p. 3741 - 3750

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被引用次数: 29

摘要

Abstract The novel furanomycin analogues 8 and 17 were synthesized as mixture of two diastereomers using the gold-catalyzed cycloisomerization of α-hydroxyallenes as the key step. Compared to the traditional use of stoichiometric amounts of silver salts, gold catalysis is much more efficient for the cyclization of highly functionalized substrates.