前往化源商城

Tetrahedron

Vinyl anion equivalent V. Asymmetric synthesis of allylic alcohols using chiral 2-(trialkylsilyl) ethyl sulfoxides

S Kusuda, Y Ueno, T Toru

文献索引:Kusuda, Shinya; Ueno, Yoshio; Toru, Takeshi Tetrahedron, 1994 , vol. 50, # 4 p. 1045 - 1062

全文:HTML全文

被引用次数: 28

摘要

Both enantiomers of optically pure secondary allylic alcohols can be conveniently prepared by the diastereoselective reaction of the α-sulfinyl carbanion of p-tolyl 2-(trialkylsilyl) ethyl sulfoxides or tert-butyl 2-(trimethylsilyl) ethyl sulfoxide with aldehydes followed by either fluoride-induced desilylsulfinylation or thermal elimination of the sulfinyl group.