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Evolution of a series of peptidoleukotriene antagonists: synthesis and structure/activity relationships of 1, 3, 5-substituted indoles and indazoles

VG Matassa, TP Maduskuie Jr…

文献索引:Journal of Medicinal Chemistry, , vol. 33, # 6 p. 1781 - 1790

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被引用次数: 92

摘要

... The discovery of potent and selective peptidoleukotriene (LTC,, LTD,, and LTE,) antagonists for the treatment of asthma, and other allergic conditions, remains a major focus for pharmaceutical research. ... Page 2. 1782 Journal of Medicinal Chemistry, 1990, Vol. 33, No. ...