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Novel frameworks for trifluoromethyl ketone and phosphonate tsa inhibitors of type II PLA 2

RS Garigipati, G Seibel, RJ Mayer, B Bolognese…

文献索引:Garigipati, Ravi S.; Seibel, George; Mayer, Ruth J.; Bolognese, Brian; McCord, Mark; Marshall, Lisa A.; Adams, Jerry L. Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 11 p. 1421 - 1426

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摘要

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Design and synthesis of some TSA inhibitors on novel molecular frameworks is described. This TSA analog design culminates in the preparation of the phosphonate 18. ... The design and synthesis of some TSA inhibitors for s-PLA 2 are described. Our approach, which makes ...