Novel lead generation through hypothetical pharmacophore three-dimensional database searching: Discovery of isoflavonoids as nonsteroidal inhibitors of rat 5α- …
GS Chen, CS Chang, WM Kan, CL Chang…
文献索引：Igarashi, Susumu; Inami, Hiroshi; Hara, Hiromu; Fujii, Masahiro; Koutoku, Hiroshi; Oritani, Hiroyuki; Mase, Toshiyasu Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 3 p. 382 - 388
... Journal of Medicinal Chemistry. ... active compounds 1, 2, 4, and 5 to validate our model in view of the fact that they possessed different chemical structures. ... Hence, Igarashi's two potent compounds 4-(biphenyl-4-yloxy)chlorobenzoic acid (18a) and 4-[(1-benzyl-1H-indol-5-yl)oxy]- ...
