Typical procedure: Appropriate solvent (25 ml, Table) was treated at room temperature with catalyst (7.5–10 mmol), followed by the addition of the corresponding C 3 synthon 2 – 5 (7.5 mmol) and carboxamide oxime 1 (7.2 mmol). Reaction mixture was heated under reflux, evaporated to dryness, dissolved in water, neutralized with sodium carbonate, extracted with chloroform, dried over anhydrous sodium sulfate and evaporated to dryness. Pyrimidine 1-oxides have ...
