Synthesis of fluorinated 2-phenyl-4-quinolones from pyrrole-2, 3-diones

VVR Rao, C Wentrup

文献索引：Rao, V. V. Ramana; Wentrup, Curt Journal of the Chemical Society, Perkin Transactions 1, 2002 , # 10 p. 1232 - 1235

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被引用次数: 19

摘要

A series of substituted 2-phenyl-4-quinolones 8–11 have been synthesized in good yields via flash vacuum thermolysis (FVT) of 1-aryl-4-cyano-5-phenylpyrrole-2, 3-diones 7a–e and 1-aryl-4-methoxycarbonyl-5-phenylpyrrole-2, 3-diones 7f–j. The pyrrolediones 7 were prepared from amines 3 and benzoylacetonitriles 5a–e or methyl 3-arylamino-3-phenylprop- 2-enoates 5f–j.