Highly diastereoselective alkylations of chiral amide enolates: new routes to hydroxyethylene dipeptide isostere inhibitors of HIV-1 protease
…, MA Wallace, JP Vacca, RA Reamer…
文献索引：Askin, D.; Wallace, M. A.; Vacca, J. P.; Reamer, R. A.; Volante, R. P.; Shinkai, I. Journal of Organic Chemistry, 1992 , vol. 57, # 10 p. 2771 - 2773
The combination of great effectiveness and ready availability should make the new phthalazine cinchona derivatives 1 and 2 the AD'S workhorse ligands for some time to come. Nevertheless, terminal olefins are the most common and important members of the olefin family and since most representatives are still below the 90% ee level (Table I, entries 7-12), the search for new ligands con- tinues. ... Acknowledgment. Financial support was provided by the ...
