Simple Phase Transfer Catalytic Method for α-Methoxylation of Sterically Hindered Ketones

…, K Rubina, M Shymanska, E Lukevics

文献索引：Abele; Rubina; Shymanska; Lukevics Synthetic Communications, 1995 , vol. 25, # 9 p. 1371 - 1376

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被引用次数: 3

摘要

Abstract Reactions of sterically hindered ketones of ArylCOCHR1R2 type (R1, R2= Me, Et, Ph) with carbon tetrachloride and methyl iodide in the presence of solid KOH and 18-crown- 6 afford the corresponding α methoxyketones [ArylCOC (OMe) R1R2] in one-pot process in 30–67% yields.