Synthesis of C2-C3'N-linked macrocyclic taxoids. Novel docetaxel analogues with high tubulin activity

O Querolle, J Dubois, S Thoret, F Roussi…

文献索引：Journal of Medicinal Chemistry, , vol. 47, # 24 p. 5937 - 5944

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被引用次数: 34

摘要

... Journal of Medicinal Chemistry. ... linked to the ortho-, meta-, or para-position of the C2-aromatic ring (Figure 2). Chemistry. The synthesis of compounds 4 has been realized by using the same strategy as for compounds ...