The biaryl linkage is an important structural motif in several natural products and bioactive compounds. 1 It is also a critical structural component of axially dissymmetric ligands that are used extensively with various metals in homogeneous enantioselective catalysis. The Suzuki–Miyaura coupling reaction is a powerful and widely used method for the synthesis of biaryls. 2 Allyl and vinyl halides, similarly, can be coupled with boronic acids to afford ...
