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Journal of medicinal chemistry

Synthesis and antiviral activity of some acyclic and C-acyclic pyrrolo [2, 3-d] pyrimidine nucleoside analogs

SM Bennett, NB Nghe, KK Ogilvie

文献索引:Bennett, Sharon M.; Nguyen-Ba, Nghe; Ogilvie, Kelvin K. Journal of Medicinal Chemistry, 1990 , vol. 33, # 8 p. 2162 - 2173

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被引用次数: 49

摘要

Pyrrolo [2, 3-d] pyrimidine nucleosides have been the subject of a number of scientific studies since the report of the pronounced biological activity of some of these nucleosides.'In fact, the antiviral activity of several of the naturally occurring pyrrolo [2, 3-d] pyrimidine nucleosides, and of some of their analogues, has been well documenteda2 These natural products are commonly referred to as the 7-deazapurines and some representative ...