A new synthetic route to the previously unattainable 2-arylpyrido [2, 3-b][1, 5] thiazepin-4 (5H)-ones

A Couture, E Huguerre…

文献索引：Couture, A.; Huguerre, E.; Grandclaudon, P. Journal of Organic Chemistry, 1990 , vol. 55, # 14 p. 4337 - 4339

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被引用次数: 8

摘要

In recent years members of the benzothiazepinone class of compounds have generated considerable interest owing to their remarkable diversity of biological activity. In particular, the 2-aryl-1, 5-benzothiazepin-4 (5H)-one skeleton constitutes the framework of several biologically active compounds, eg, antidepressants like Thiazesim,'coronary vasodilators like Diltia~ em,~~~ and antiulcer and antisecretory agents such as BTM-1086.4 ...