Pd (OAc) 2 in combination with the commercially available ligand P (i-BuNCH2CH2) 3N catalyzes the Suzuki cross-coupling reaction of a wide variety of aryl bromides and chlorides with arylboronic acids, affording the desired biaryls in excellent yields. It has also been shown that P (NMe2) 3 can be employed as a ligand, though with significantly more limited success.