Tetrahedron

Asymmetric synthesis of 3 (S), 17-dihydroxytanshinone

J Zhang, W Duan, J Cai

文献索引：Zhang, Jiangang; Duan, Wenhu; Cai, Junchao Tetrahedron, 2004 , vol. 60, # 7 p. 1665 - 1669

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被引用次数: 14

摘要

The first synthesis of 3 (S), 17-dihydroxytanshinone was achieved by ultrasound promoted Diels–Alder reaction of the protected 3-hydroxymethyl-4, 5-benzofurandione with a vinylcyclohexene derivative. Bioassay showed that the synthetic 3 (S), 17- dihydroxytanshinone was active in vitro against HL-60 tumor cell line by MTT method.