The Journal of Organic Chemistry

Catalyzed reaction of diazodiphenylethanone and related diazo ketones with enaminones as a source of pyrroles

MN Eberlin, C Kascheres

文献索引：Eberlin, Marcos N.; Kascheres, Concetta Journal of Organic Chemistry, 1988 , vol. 53, # 9 p. 2084 - 2086

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被引用次数: 55

摘要

The reaction of copper (I1)-stabilized keto carbenes (1, 7, S), derived from diazo ketones, with enaminones leads to the formation of pyrroles. The cyclic enaminones 3 react with the keto carbenes on nitrogen to form products 5, 9, 11, and/or pyrroles 6, 10, and 12. Treatment of the initially formed addition products 5, 9, and 11 with KOH in ethanol leads to formation of the corresponding pyrroles for the cyclic six-membered enaminones 3a, c but not for the ...