Isoxazoles and its derivatives represent useful synthetic building blocks1. They are an important class of heterocycles compounds, which are employed in the area of pharmaceuticals and therapeutic such as antimicrobial, antifungal2, anticancer3, ulcerogenic4 and anti-inflammatory5. Therefore, various synthetic methods have been reported to access the isoxazole derivatives6. Multicomponent coupling reactions (MCRs) involving domino processes, in ...
