Tetrahedron: Asymmetry

Enzyme assisted preparation of enantiomerically pure β-adrenergic blockers II. Building blocks of high optical purity and their synthetic conversion

U Ader, MP Schneider

文献索引：Ader, Ulrich; Schneider, Manfred P. Tetrahedron: Asymmetry, 1992 , vol. 3, # 2 p. 205 - 208

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被引用次数: 42

摘要

Abstract Based on previous screening results a series of potential building blocks t2–4 for β- adrenergic blockers were prepared both by enzymatic hydrolysis and acyltransfer and further transformed into the corresponding oxiranes and aminoalcohols of defined absolute configurations.