Design, Synthesis, and Characterization of SO2-Containing Azabicyclo [3. n. 1] alkanes: Promising Building Blocks for Drug Discovery

T Druzhenko, O Denisenko, Y Kheylik, S Zozulya…

文献索引：Goh, Yi Ling; Tam, Eric K.W.; Bernardo, Paul H.; Cheong, Choon Boon; Johannes, Charles W.; William, Anthony D.; Adsool, Vikrant A. Organic Letters, 2014 , vol. 16, # 7 p. 1884 - 1887

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被引用次数: 8

摘要

... Organic Letters. ... Indeed, ketone 3 was previously comprehensively described in the literature by a standard Mannich reaction of 1, however, with yields of only 38–48%.(11) Oxidation of 3 with H 2 O 2 in acetic acid afforded the target core 4 in 58% yield. ...