Bioorthogonal imaging of aurora kinase A in live cells

KS Yang, G Budin, T Reiner, C Vinegoni…

文献索引：Yang, Katherine S.; Budin, Ghyslain; Reiner, Thomas; Vinegoni, Claudio; Weissleder, Ralph Angewandte Chemie - International Edition, 2012 , vol. 51, # 27 p. 6598 - 6603

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被引用次数: 43

摘要

Cell division (mitosis) is a tightly controlled process that is coordinated and regulated by a network of proteins localized in the nucleus. The key stages of mitosis are centrosome maturation, chromosome condensation, nuclear envelope breakdown, centrosome separation, bipolar spindle formation, chromosome separation, and finally cytokinesis.[1] Aurora kinaseA (AKA) belongs to the Aurora kinase family of serine/threonine kinases, ...