A nitrone-based approach to the enantioselective total synthesis of (-)-anisomycin

R Ballini, E Marcantoni, M Petrini

文献索引：Ballini, Roberto; Marcantoni, Enrico; Petrini, Marino Journal of Organic Chemistry, 1992 , vol. 57, # 4 p. 1316 - 1318

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被引用次数: 129

摘要

It has been shown to act as an inhibitor of protein~ ynthesis,~ and it finds wide use in the treatment of trichomonas vaginitis and amebic dysentery. Its absolute configuration was definitively established in 1968 by chemical correlation with tyrosine.^ Several chiral syntheses of (-)-anisomycin have appeared in literature for the most part employing naturally occurring starting materials such as carbohydrate^,^ amino acids: and L-tartaric acid or its ...