Synthesis and biological activity of 2 (3)-dialkylphosphonoalkyl acetates

…, GV Strel'tsova, NP Matyukhova, VN Nazarenko…

文献索引：Brel', A. K.; Tyurenkov, I. N.; Strel'tsova, G. V.; Matyukhova, N. P.; Nazarenko, V. N.; Agarkova, N. S. Pharmaceutical Chemistry Journal, 1988 , vol. 22, # 2 p. 118 - 120 Khimiko-Farmatsevticheskii Zhurnal, 1988 , vol. 22, # 2 p. 167 - 170

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被引用次数: 1

摘要

A number of examples of this reaction are described in the literature, but the low yields of desired products and the long reaction times do not allow it to recommend them as preparative methods of synthesis. The reaction mechanism consists in the homolytic addition of the dialkyl phosphltes to the multiple bond. Initiators used earller did not make it possible to obtain the dialkylphosphonoalkyl acetates in high yields. For example, ben-. ...