Diaryl Sulfoxides from Aryl Benzyl Sulfoxides: A Single Palladium??Catalyzed Triple Relay Process

T Jia, A Bellomo, S Montel, M Zhang…

文献索引：Jia, Tiezheng; Bellomo, Ana; Montel, Sonia; Zhang, Mengnan; El Baina, Kawtar; Zheng, Bing; Walsh, Patrick J. Angewandte Chemie - International Edition, 2014 , vol. 53, # 1 p. 260 - 264 Angew. Chem., 2014 , vol. 126, # 1 p. 264 - 268,5

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被引用次数: 33

摘要

Abstract A novel approach to produce diaryl sulfoxides from aryl benzyl sulfoxides is reported. Optimization of the reaction conditions was performed using high-throughput experimentation techniques. The [Pd (dba) 2]/NiXantPhos catalyst system successfully promotes a triple relay process involving sulfoxide α-arylation, C [BOND] S bond cleavage, and C [BOND] S bond formation. The byproduct benzophenone is formed by an additional ...