... The poor analgetic activity of this coni- pound could be directly correlated with its very poor gastrointestinal absorptions determined by the method of Hogben, et al.9 It is noteworthy that ring methyla- (7) P. Schwerin, SP Bessman, and H. Waelsch, J. Bid. Chem., 184, 37 (1950). ... The crystal- line previpitate was filtered off and dissolved in wat,er. The pH of the result,iiig solut,ioii was adjueted t,o 3.2 with 10%; NaOH. ... (b) see also H. Dubicki. F. Zielinaki, and I:. IV. ...