Design and synthesis of brain penetrant selective JNK inhibitors with improved pharmacokinetic properties for the prevention of neurodegeneration

S Bowers, AP Truong, RJ Neitz, RK Hom…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 18 p. 5521 - 5527

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被引用次数: 17

摘要

... Bioorganic & Medicinal Chemistry Letters. ... a Department of Chemical Sciences, Elan Pharmaceuticals, 180 Oyster Point Boulevard, South San Francisco, CA 94080, United States; b Department of Molecular Design, Elan Pharmaceuticals, 180 Oyster Point Boulevard, South ...