Multicomponent Approach Towards the Synthesis of Substituted Pyrroles under Supramolecular Catalysis Using β??Cyclodextrin as a Catalyst in Water Under Neutral …
Abstract Synthesis of substituted pyrroles in H 2 O by using β-cyclodextrin as a supramolecular catalyst is described. This reaction has several advantages over existing methods and provides substituted pyrroles in good-to-excellent yields (79–89%). The supramolecular catalysis of the reaction was studied using 1 H-NMR spectroscopy. β- Cyclodextrin can be recovered and reused several times without loss of activity.