Organic letters

Ruthenium (II) porphyrin-catalyzed amidation of aromatic heterocycles

L He, PWH Chan, WM Tsui, WY Yu, CM Che

文献索引：He, Ling; Chan, Philip Wai Hong; Tsui, Wai-Man; Yu, Wing-Yiu; Che, Chi-Ming Organic Letters, 2004 , vol. 6, # 14 p. 2405 - 2408

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被引用次数: 57

摘要

Ruthenium (II) porphyrin-catalyzed amidation of aromatic heterocycles with iminoiodanes under mild conditions (CH2Cl2, 4 Å molecular sieves, ultrasound, 40° C) was achieved in moderate to good yields (up to 84%) and conversions (up to 99%). Only the N, N- ditosylamidated product was obtained for reactions involving heteroarenes, where X= O, S, or NTs. N-Alkyl-and N-aryl-substituted pyrroles, on the other hand, were shown to give the ...