Organic letters

Domino processes as a tool for recovering substandard reactions. Synthesis and use of nitroacetic acid esters and amides

N Scardovi, A Casalini, F Peri, P Righi

文献索引：Scardovi, Noemi; Casalini, Andrea; Peri, Francesca; Righi, Paolo Organic Letters, 2002 , vol. 4, # 6 p. 965 - 968

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被引用次数: 21

摘要

Elusive nitroacetic acid esters and amides were obtained through a halogen exchange reaction of the corresponding bromoacetic acid derivatives with polymer-supported nitrite anion. The process is flawed by a side product catalyzed degradation of the products. Domino processes turned out to be a powerful tool for overcoming such drawbacks, converting a substandard reaction into an efficient multicomponent preparation of 4- ...