Method B. N-[5-[[(Cyclohexylamino) carbonyl] oxy]-2-pentyllnorepinephrine Hydrochloride (14). A solution of compound 28 (1 g, 4.4 mmol), dl-norepinephrine hydrochloride (903 mg, 4.4 mmol), and NaCNBH3 (416 mg, 6.6 mmol) in 35 mL of MeOH was adjusted to pH 6.0 by the additxion of HOAc. The solution was then stirred for 15 h at 40" C and then at room temperature for 36 h. Excess NaCNBH, was then destroyed by the addition of 50 mL of 0.1 ...
