Synthesis, characterization, in vitro and molecular docking studies of new 2, 5-dichloro thienyl substituted thiazole derivatives for antimicrobial properties
…, CG Darshanraj, BR Bharath, H Manjunatha
文献索引：Sarojini, Balladka Kunhanna; Krishna, Bettadapura Gundappa; Darshanraj, Chenna Govindaraju; Bharath, Basavapattana Rudresh; Manjunatha, Hanumanthappa European Journal of Medicinal Chemistry, 2010 , vol. 45, # 8 p. 3490 - 3496
A new series of 2-substituted 4-(2, 5-dichloro thienyl)-1, 3-thiazoles are synthesized by the reaction of 2-bromo-1-(2, 5-dichlorothien-3-yl) ethanone with thiourea and substituted thioamides. The newly synthesized compounds 4a–e are characterized by analytical 1H NMR, 13C NMR and mass spectral data. The newly synthesized compounds are screened for antifungal and antibacterial activities. Among them 4a and 4d exhibited good ...
